Subiculum neurons map axis of travel

New work from the Nitz laboratory demonstrates that subiculum neurons encode axis of travel along interconnected routes within an environment. Axis encoding is anchored to distal cues as revealed by 90-degree rotations of the track (see figure below). This latter fact indicates that subiculum may align familiar routes with the constellation of distal landmarks defining allocentric space.

Spatial frame of reference for axis tuning.

Olson et al., Nature Neuroscience, 2016

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